醫(yī)學生理學

內(nèi)容概要

　　自1956年第1版出版以來，《醫(yī)學生理學》每5年修訂1次，歷經(jīng)五十余年?，F(xiàn)已成為世界范圍內(nèi)的權威生理學教科書。最新的第l2版依然延續(xù)了“用最簡明的語言講述生理學核心知識”的編寫傳統(tǒng)，并特別加入了近年來重要的最新進展，涉及心血管、神經(jīng)、消化系統(tǒng)的生理學及分子生物學內(nèi)容。第12版的另一特色是將學生“必須要掌握"和“最好能掌握”的知識進行區(qū)分，“最好能掌握”的內(nèi)容以灰色陰影進行標示，以適應不同學生的需要，進一步提升了本書的易用性。

作者簡介

作者：（美國）霍爾（John E.Hall）

書籍目錄

Introduction to Physiology: The Cell and General
Physiology
Membrane Physiology, Nerve, and Muscle
The Heart
The Circulation
The Body fluids and kidneys
Respiration
Aviton,space,and deep-sea diving physiology
The Nervous System: A. General Principles and Sensory
Physiology
The Nervous System: B. The Special Senses
The Nervous System: C. Motor and Integrative Neurophysiology
Gastrointestinal Physiology
Metabolism and Temperature Regulation
Endocrinology and Reproduction
Sports physiology
Index

章節(jié)摘錄

版權頁：   插圖：   Treatment of Decompensation. The decompen-sation process can often be stopped by (1) strengthen-ing the heart in any one of several ways, especially byadministration of a cardiotonic drug, such as digitalis,so that the heart becomes strong enough to pump ade-quate quantities of blood required to make the kidneysfunction normally again, or (2) administering diureticdrugs to increase kidney excretion while at the same timereducing water and salt intake, which brings about a bal-ance between fluid intake and output despite low cardiacoutput. Both methods stop the decompensation process by re-establishing normal fluid balance so that at least as muchfluid leaves the body as enters it. Mechanism of Action of the Cardiotonic DrugsSuch as Digitalis. Cardiotonic drugs, such as digitalis,when administered to a person with a healthy heart,have little effect on increasing the contractile strengthof the cardiac muscle. However, when administered to aperson with a chronically failing heart, the same drugscan sometimes increase the strength of the failing myo-cardium as much as 50 to 100 percent. Therefore, theyare one of the mainstays of therapy in chronic heartfailure. Digitalis and other cardiotonic glycosides arebelieved to strengthen heart contractions by increasingthe quantity of calcium ions in muscle fibers. This effectis likely due to inhibition of sodium-potassium ATPasein cardiac cell membranes. Inhibition of the sodium-potassium pump increases intracellular sodium concen-tration and slows the sodium-calcium exchange pump,which extrudes calcium from the cell in exchange forsodium. Because the sodium-calcium exchange pumprelies on a high sodium gradient across the cell mem-brane, accumulation of sodium inside the cell reducesits activity. In the failing heart muscle, the sarcoplasmic reticu-lum fails to accumulate normal quantities of calciumand, therefore, cannot release enough calcium ions intothe free-fluid compartment of the muscle fibers to causefull contraction of the muscle. The effect of digitalis todepress the sodium-calcium exchange pump and raisecalcium ion concentration in cardiac muscle provides theextra calcium needed to increase the muscle contractileforce. Therefore, it is usually beneficial to depress the cal-cium pumping mechanism a moderate amount using dig-italis, allowing the muscle fiber intracellular calcium levelto rise slightly.

編輯推薦

《國外經(jīng)典醫(yī)學教材改編影印系列?雙語教材:醫(yī)學生理學(第12版)(供醫(yī)學各專業(yè)本科生、留學生、長學制、研究生雙語教學使用)》本著“用最簡明的語言講述生理學核心知識”的原則編寫，特別加入了近年來重要的最新進展，涉及心血管、神經(jīng)、消化系統(tǒng)的生理學及分子生物學內(nèi)容。

圖書封面

圖書標簽Tags

無

評論、評分、閱讀與下載

---

    醫(yī)學生理學 PDF格式下載

---