硒缺乏、毒性、生物營養(yǎng)強化與人體健康

前言

The urgent need to synthesize, critically analyze information on selenium research conducted world-wide into an updated perspective for preserving the health of the environment, livestock, and humans provided the impetus for the development of this proceedings. The book of "Selenium Deficiency, Toxicity, and Biofortification for Human Health" contains the peer-reviewed key extended abstracts to the First International Conference on Selenium in the Environment and Human Health that will be held on 18-21 October 2009 in Suzhou, China. At this conference, participants will discuss the impact of selenium contamination and deficiency on the environment, domestic animal-crop-human accumulation, biochemical metabolism processes and further on human health. The importance of these topics clearly shows why selenium is arguably the natural-occurring trace element of greatest impact worldwide in the 21st century.With the gracious financial support provided by China-Singapore Suzhou Industrial Park, Suzhou Dushu Lake Higher Education Town, Chinese Academy of Sciences, National Science Foundation of China, and Setek Co., Ltd., we are able to invite eminent scientists from within the world selenium community to provide new insight into complex-related environmental, biological, biochemical and health issues related to selenium. Symbolically we meet in China, a country that truly recognizes selenium toxicity and deficiency in human health. With authors from 1 2 countries （including Australia, Belgium, Brazil, China, Denmark, Germany, India, Poland, Sweden, Switzerland, UK, and USA）, a total of 54 presentations have been included in this publication that clearly demonstrate the significant role that selenium plays in today's modern life.

內容概要

《硒缺乏、毒性、生物營養(yǎng)強化與人體健康(英文版)》內容簡介：The urgent need to synthesize, critically analyze information on selenium research conducted world-wide into an updated perspective for preserving the health of the environment, livestock, and humans provided the impetus for the development of this proceedings.

作者簡介

編者：(美國)巴紐艾洛斯(Gary S.Banuelos) 林志清 尹雪斌

書籍目錄

Section Ⅰ: Selenium in the EnvironmentSelenium in the EnvironmentSelenium Speciation and Mobility in Soil-An OverviewPathways and Fate of Selenium in Aquatic/Terrestrial SystemsSelenium Distribution, Characterization and Partitioning in Rice Grown in ChinaThe Development of Risk Maps Using Statistical Models: Selenium Deficiency in SoilsBiological Endpoints of Selenium Deficiency & ToxicitySelenium Toxicity and Daily Selenium Intake in Enshi, ChinaSelenium Toxicity to Animals and Humans in Northwestern India-A Case StudyStudy of Content of Selenium in Coals from Baishan Coal Mine in Huaibei of Anhui, ChinaAmelioration and Conversion of Excessive Selenium to New Resources from a Plant-Based SystemBioremediation of SeleniumGE ABMet (Advanced Biological Metals Removal): Setting the Standard for Selenium Removal in Flue Gas Desulfurization WastewaterSpeciation of Selenium in Animal Feed (Squid Meal and Fish Meal) by HPLC-ICP-MSImproved Selenium Status by Consumption of Wheat Biofortified with Selenium Does Not Modify DNA Damage in Lymphocytes of Healthy Older Australian MenA Preliminary Investigation of Selenium-Accumulated Plants in Enshi City, Hubei Province, ChinaDistribution of Selenium in Residue Landfill and Surroundings from a Chinese Electrolytic Manganese Metals (EMM) IndustryRemoving Excessive Selenium from Water Using Modified Filter MediaRemoving Selenium from Raw Water Using Activated Carbon AdsorptionMercury-Selenium Association in Antarctic Seal tiairs and Animal Excrements over the Past 1,500 YearsSection Ⅱ: Effects of Selenium on Human and Animal HealthNet Mineralization Rate of Selenium from Plant Material and Inorganic SaltsSelenium Metabolism and Selenoproteins in Human HealthCan Selenium Play a Role in Cancer Prevention? Methyl Selenocysteine PharmacodynamicsSelenoprotein Synthesis and Reactivity-Biotechnologieal and Biomedical ApplicationsEffect of Substituted Organoselenium Compounds on Free Radical Induced Liver Mitochondrial DysfunctionEffects of Deoxynivaleno[, Nivaleno[, T-2 Toxin and Selenium on the Metabolism of Tissue Engineered Cartilage In VitroThe Role of Selenium in Fetal Development and Animal HealthSignificance of Elevated Selenium in Muscle Tissue: Functional Food and Nutrient Reserve?Effects of Different Selenium Sources on Antioxidant Status and Productive Performance in SowBiological effects of Different Selenomethionine Forms and Levels on Breeder Hens and Their OffspringEffects of Hydrogen Peroxide on 15-kDa Selenoprotein Transcription and TranslationImmunomodulatory and Anti-inflammatory Activities of Novel Organoselenium Compounds against Helicobacter pylori InfectionSection Ⅲ: Selenium BiofortificationRegulatory and Legal Considerations for the Production and Sale Selenium-Enriched Foods-the Example of the United StatesJ.W.FinleyEfficiency of Selenium Uptake from a Belgian Soil Treated with a Commercial Se-Containing Fertilizer by Grass and MaizeGD. Laing, B. Vandecasteele, X. Van Doorslaer, and E TackEvidences of Selenium Deficiency in Brazil: from Soil to Human NutritionM.F. Moraes, R.M. Welch, M.R. NuttL J.L. V. Carvalho, and E. Watanabe Production of Selenium-Biofortified Cereal ProductsGH. LyonsAgronomic Biofortification of Maize (Zea rnays L.) with Selenium in MalawiA.D.C. Chilimba, CR. Black, J. Lammel, M.C Meacham, S.D. Young, and M.R. BroadleyBioactivity of Selenium-Enriched BrassicaS.E. Volker and E.H. JefferyDaily Dietary Intake of Selenium in Suzhou Industrial Park, ChinaJ. Gao, Y. Liu, Z.-Q. Lin, GS. Banuelos, M. Lain, andX.B. YinDifferences in Uptake, Translocation, Distribution and Toxicity of Selenate and Selenite by PakchoiD.L. Liang, X.P. Wu, J.D. Bao, R.L. Xue, S.S. Wang, and Z.H. WangThe Effects of Selenium Accumulation on Biochemical Composition of Rapeseed (Brassica napus)S. sharma, A. Bansal, S.K. Dhillon and K.S. DhilonThe Selenium Uptake and Accumulation in Green TeaY. Huang, ELi, and X.B. YinDetermination of Selenium Speciation in Selenium-Enriched Corn and Yeast by HPLC-UV-HG-AFSW. Wang, H.Q. Liu, Y.Y. Zhu, S.E Liu, S.B. Zhou, andX.B. YinA Study on the Determination of Selenium Speciation of High Selenium Plants in Enshi Using LC-AFSH.Q. Liu, Y.Y. Zhu, J. Gao, Y.Q. Liu, andX.B. YinDistribution of Molecular Weight of Selenoprotein Extracted from Se-enriched Brown RiceK.L. Liu and Z.X. GuEffects of Selenium and Iron on Soybean Growth and Seed Trace Element Quality Grown on Se-Deficient SoilK.Y. Li, Z.H. Wang, Y.B. Gong, Y. Zhou, andD. CuiKey Factors Influencing Selenite Uptake in Rice SeedlingsL.H. ZhangSection Ⅳ: Other Uses of SeleniumApplication of Se/CO System in Organic Synthesis: A Brief IntroductionS. W. Lu, Y. Yang, J.T. Mei, J.Z. Chen, X.P. Zhang, X.E Wang, X.Z. Liu, P, Li, and X.H. YuanSelenation Reactions with H2Se Generated by Se/CO/H20 SystemES. Tian, Y.H. Chen, and S. W. LuSynthesis of Unsymmetric Ureas by Selenium-Catalyzed Redox Carbonylation Reactions of Nitroarenes and AminesY. Yang, J.T. Mei, J.Z. Chen, G. Ling, X.H. Yuan, and S. W. LuNew Non-phosgene Routes to Pesticides by Selenium-Catalyzed Carbonylation ReactionsX.H. Yuan, J.T. Mei, Y. Yang, X.F Wang, and S.W. LuEfficient Synthesis of 1, 3-Disubstitutedimidazole-2-selonesP Li, X.F. Wang, X.H. Yuan, S.D. Wang, andS. W LuSynthesis of Carbamates/Thiocarbamates by Selenium-catalyzed Carbonylation ReactionsX.P Zhang, Y. Yang, G, Ling, X.E Wang, P Li, and S. W. LuSelective Formation of Unsymmetric Ureas by Selenium-Catalyzed Redox Carbonylation of COJ.T. Mei, Y.D. Luo, Y. Xue, and S. W LuSelenium-Catalyzed Reduction of Aromatic nitro Compounds with CO/H20 under AtmosphericPressureX.Z Liu and S. W Lu

章節(jié)摘錄

插圖：Results and Discussion Toxic effects of selenosis include thyroid hormone impairment, immune system dysfunction, hepatotoxicity, gastrointestinal disturbances, dermatological disorders, and hair loss. Typical livestock symptoms include structural abnormalities or deformities in the protein components of the hooves, hair, and/or nails. A 2007 paper suggests an associate between elevated Se levels in blood and increased incidence of diabetes in humans.Excess selenium in the food supply may result in the consumption of a potentially toxic product, as illustrated in a USA swine selenosis case study. Symptoms of selenosis were observed in animals with Se blood levels less than 1 mg L-1 and feed concentrations of about 10 mg kg-1. Feed analysis indicated the swine premix samples contained over 100 mg Se kg-1. Pork is considered safe at a Se muscle concentration of about 0.40 mg kgl wet weight.The endpoint of Se deficiency in livestock was established by the 1973 USA Food and Drug Administration Act which set the minimum Se content in livestock feeds and supplements as 3.0 mg Se kg1. However, the upper dietary recommendation for Se in livestock feeds and natural forage is 5.0 mg kg1, resulting in a narrow "safe" rangebetween deficiency and potential toxicity. Worst-cast environmental assessments are often associated with Se contaminants originating from coal fired power plants. Recently, December, 2008, at the Tennessee Valley Authority Kingston Fossil Plant, a sixty-foot ash and earthen wall securing a retention pond holding five decades of coal fly ash gave way causing a catastrophic wave of slurry.

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