出版時(shí)間:2009-1 出版社:清華大學(xué)出版社 作者:時(shí)東陸 主編 頁(yè)數(shù):711
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內(nèi)容概要
本書(shū)主要介紹了納米生物醫(yī)學(xué)研究領(lǐng)域的新進(jìn)展。本書(shū)分為三部分,第一部分?jǐn)⑹隽思{米尺度的生物材料的設(shè)計(jì)、合成、特性以及應(yīng)用,包括干細(xì)胞和相關(guān)技術(shù)、聚合體納米纖維及其生物醫(yī)學(xué)應(yīng)用、自組織生物材料及其生物醫(yī)學(xué)應(yīng)用、生物探測(cè)材料的合成和自組織、磷酸鹽陶瓷的生物領(lǐng)域的應(yīng)用、生物材料的表面和界面特性、碳納米管在生物傳感方面的應(yīng)用等;第二部分詳細(xì)介紹納米尺度的生物醫(yī)學(xué)的新技術(shù),包括藥物輸運(yùn)技術(shù)、生物醫(yī)學(xué)領(lǐng)域的微納技術(shù)、DNA技術(shù)、納米尺度的生物活性表面和移植、碳納米管智能材料在生物和醫(yī)學(xué)方面的應(yīng)用等。第三部分的重點(diǎn)是納米材料合成和結(jié)構(gòu)的最新進(jìn)展,包括納米材料中的聲子行為、納米粒子和納米流體的合成和特性的最新進(jìn)展等。 本書(shū)由工作在世界納米生物醫(yī)學(xué)領(lǐng)域的杰出科學(xué)家撰寫(xiě)。本書(shū)的讀者對(duì)象為相關(guān)專(zhuān)業(yè)高年級(jí)大學(xué)生、研究牛、科技人員、工程技術(shù)人員。
書(shū)籍目錄
1 Stem Cells and Nanostructured Materials2 Biomedical Polymer Nanofibers for Emerging Technology3 Nanoscale Mechanisms For Assembly of Biomaterials4 Fabrication and Assembly of Nanomaterials and Nanomaterials and Nanostrucures for bioological detections5 Nanostructured Materials Constructed from Polypeptides6 Photoluminescent Carbon Nanomaterials:Properties and Potential Applications7 Microwave-assisted Synthesis and Processing of Biomaterials8 Characterizing Biointerfaces and Biosurfaces in Biomaterials Design9 Carbon Nanotubes for Electrochemical and Electronic Biosensing Applications10 Heparin-Conjugated Nanoiterfeces for Biomedical Applications11 Inorganic Nanoparticles for Biomedical Applications12 Nano Metal Particles for Biomedical Applications13 Micro-and Nanoscale Technologies in High-Throughput Biomedical Experimentation14 Delivery System of Bioactive Molecules for Regenerative Medicine15 Modification of Nano-sized Materials for Drug Delivery16 Polymeric Nano Micelles as a Drug Carrier17 DNA Nanotechnology18 Nanoscale Bioactive Surfaces and Endosseous Implantology19 Carbon Nanotube Smart Materials for Biology and Medicene20 Microscopic Modeling of Phonon Modes in Semiconductor Nanocrystals21 Fracture Processes in Advanced Nanocrystalline22 Synthesis,Properties and Application of Conducting PPY Nanoparticles23 Field Emission of Carbon Nanotubes24 Flexible Dye-Sensitized Nano-Porous Films Soar Cells25 Magnetic Nanofluids:Synthesis and Structure
章節(jié)摘錄
插圖:Peptides provide an attractive profile of materials properties that make themunique building blocks for nanoscale materials。Because aqueous self-assemblyprocesses are employed in many materials applications of peptides,these materialstend to be sensitive to pH,ionic strength,temperature,and other factors fromwhich stimulus-responsive strategies can be built.Moreover,peptide materialscan be bioactive,particularly when their design mimics functional elements ofnative proteins.Additionally,being accessible synthetically,peptide materials areby nature easily tailored,and the materials from which they are built arelikewisehighly engineerable.This aspect arises from these materials’inherent modularity.5.4.1 Stimulus.ResponsivenessGiven that many peptide-based materials are constructed through peptide foldingand aqueous self-assembly,the factors that govem these processes are convenienttriggers for rapidly altering the properties of these materials.Self-assemblymechanisms are covered in depth in this book in the chapter by Sui and Murphyentitled‘Nanoscale Mechanisms for Assembly of Biomaterials’.In particular,self-assembly iS sensitive to pH,ionic strength,temperature,and CO.solvents.Stimulus-responsiveness IS a usefu!property that enables such applications astriggered release of drug payloads,injectable gels for minimally invasive surgery,or tnosensmg,where changes in the sensing environment trigger large scalechanges m the properties of the material.Here we will provide a few examples ofPcptide-based materials that employ such strategies.For a more complete reviewof stimulus.responsive peptide-based biomaterials,see(Mart et a1.2006). In 13-sheet fibrils,many strategies for producing stimulus.sensitive materialshave capitalized on the sensitivity of p.sheet fibril assembly to the presence ofsalts.As described in Sec.5.3.1,p.sheet fibrillization is dramatically acceleratedwhen salts are present in solution.
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《納米生物醫(yī)學(xué)》由工作在世界納米生物醫(yī)學(xué)領(lǐng)域的杰出科學(xué)家撰寫(xiě)。《納米生物醫(yī)學(xué)》的讀者對(duì)象為相關(guān)專(zhuān)業(yè)高年級(jí)大學(xué)生、研究牛、科技人員、工程技術(shù)人員。
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