真核生物轉(zhuǎn)錄調(diào)控概念，策略和方法

內(nèi)容概要

本書描述了真核生物的基因轉(zhuǎn)錄調(diào)控過程中的分子機(jī)理，分析啟動(dòng)子和轉(zhuǎn)錄因子以及其他與真核基因轉(zhuǎn)錄調(diào)控有關(guān)的研究路線和實(shí)驗(yàn)技術(shù)。

書籍目錄

1 A PRIMER ON TRANSCRIPTIONAL REGULATION IN MAMMALIAN CELLS
2 INITIAL STRATEGIC ISSUES
3 MODES OF REGULATING mRNA ABUNDANCE
4 TRANSCRIPTION INTIATION SITE MAPPING
5 FUNCTIONAL ASSAYS FOR PROMOTER ANALYSIS
6 IDENTIFICATION AND ANALYSIS OF DISTANT CONTROL REGIONS
7 IDENTIFYING cis-ACTING DNA ELEMENTS WITHIN A CONTROL REGI
N_8 IDENTIFICATION OF DNA-BINDING PROTEINS AND ISOLATION OF THEIR GENES
9 CONFIRMING THE FUNCTIONAL IMPORTANCE OF A PROTEIN-DNA INTERACTI
N_10 IN VIVO ANALYSIS OF AN ENDOGENOUS CONTROL REGI
N_11 APPROACHES FOR THE SYNTHESIS OF RECOMBINANT TRANSCRIPTION FACTORS
12 IDENTIFYING AND CHARACTERIZING TRANSCRIPTION FACTOR DOMAINS
13 THEORY，CHARACTERIZATION，AND MODELING OF DNA BINDING BY REGULATORY TRANSCRIPTION FACTORS
14 CRUDE AND FRACTIONATED SYSTEMS FOR IN VITRO TRANSCRIPTI
N_15 APPROACHES FOR STUDYING TRANSCRIPTION COMPLEX ASSEMBLY
APPENDICES
INDEX

圖書封面

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