血液病分子生物學(xué)

內(nèi)容概要

"Since the second deitoin of this book was published in 1994, knowledge of the molecular basis of blood diseases has grown exponentially. This is reflected in the contents of the trird edition of the book. Seven new chapters, on Stem Cell Biology, on Hematopoiectic Growth Factors and Rceptors, on Hematopoietic Transcriptional Factors, on Signal Transduction in the Regulation of Hematopoiesis, on Integrins in Hematology, on Paroxysmal Nocturnal Hemoglobinuria, and on Gene Therapy of Blood Diseases, have been added. All other chapters have been rewritten or extensively updated to relfect the explosion of knowledge. The first two deitions extablished The Molecular Basis of Blood Disases as a very useful resource for all individuals with an interest in hematology. We hope that the expanded and extensively updated third edition will be useful to a diverse audience, including established updated third edition will be useful to a diverse audience, including established scientists, individuals engaged in teaching and the practice of hematology, postdoctoral fellows, and residents as well as medical and graduate students."

書籍目錄

Part Ⅰ Hematopoiesis Chapter 1  STEM CELL BIOLOGY Chapter 2  HEMATOPOIETIC GROWTH FACTORS AND RECEPTORS Chapter 3  TRANSCRIPTION FACTORS THAT REGULATE LINEAGE DECISIONS Chapter 4  SIGNAL TRANSDUCTION IN THE REGULATION OF HEMATOPOIESISPart Ⅱ Red Cells Chapter 5  HEMOGLOBIN SWITCHING Chapter 6  THE THALASSEMIAS Chapter 7  HUMAN HEMOGLOBINS:SICKLE HEMOGLOBIN AND OTHER MUTANTS Chapter 8  THE ERYTHROCYTE MEMBRANE AND CYTOSKELETON:STRUCTURE,FUNCTION,AND DISORDERS Chapter 9  RED CELLL MEMBRANE ANTIGENS Chapter 10  MOLECULAR BASIS OF IRON METABOLISMPart Ⅲ Lymphopoiesis Chapter 11  GENE REARRANGEMENTS IN LYMPHOID CELLS Chapter 12  LYMPHOCYTE DEVELOPMENT Chapter 13  ANTIGEN PROCESSING AND T-CEL EFFECTOR MECHANISMSPart Ⅳ Myelopoiesis/White Blood Cells Chapter 14  INTEGRINS IN HEMATOLOGY Chapter 15  CHEMOKINES AND THEIR RECEPTORS Chapter 16  GENETIC DISORDERS OF PHAGOCYTE KILLING Chapter 17  PAROXYSMAL NOCTURNAL HEMOGLOBINURIAPart Ⅴ Hemostasis Chapter 18  VITAMIN K-DEPENDENT PROTEINS IN BLOOD COAGULATION Chapter 19  THE PROTEIN C ANTICOAGULANT SYSTEM Chapter 20  REGULATION OF BLOOD COAGULATION BY PROTEASE INHIBITORS Chapter 21  HEMOPHILA A,HEMOPHILIA B,AND VON WILLEBRAND DISEASE Chapter 22  THE MOLECULAR BASIS OF FIBBIN Chapter 23  FIBRINOLYSIS AND THE CONTROL OF HEMOSTASIS Chapter 24  PLATELETSPart Ⅵ Molecular OncologyPart Ⅶ VirusesPart Ⅷ Gene TherapySUMMARYINDEX

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