化學(xué)生物學(xué)

出版時(shí)間:2007-7  出版社:科學(xué)出版社  作者:布蘭查德  頁(yè)數(shù):193  
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內(nèi)容概要

《生命科學(xué)新視野》叢書精選Trends、Current Opinion和Drug Discovery Today等系列出版物中的部分最新論文,以原文稍加中文注解的形式,按專題編輯成冊(cè)。本書為其中一冊(cè),共有25篇文章,主要涉及生物催化、生物轉(zhuǎn)化、人工進(jìn)化等內(nèi)容。    本書將主要面向大學(xué)高年級(jí)學(xué)生、教師、研究生以及科研工作者,供其參考和收藏。

書籍目錄

中文摘要化學(xué)生物學(xué)Enzymatic tools for engineering natural product glycosylationSophie Blanchard and Jon S Thorson天然產(chǎn)物糖基化的工具酶Nucleic acid aptamers and enzymes as sensorsNaveen K Navani and Yingfu Li作為傳感器的核酸適配子和酶Catalytic antibodies and their applicationsCarl Veith Hanson,Yasuhim Nishiyama and Sudhir Paul催化抗體及其應(yīng)用The evolution of DNA polymerases with novel activitiesAllison A Henry and Floyd E Romesberg新活性DNA聚合酶的人工進(jìn)化Understanding enzyme action on immobilised substratesPeter J Hatling,Rein V Ulijn and Sabine L Flitsch酶對(duì)固定化底物的作用Mining genomes and‘metagenomes’for novel catalystsManuel Ferrer,F(xiàn)rancisco Ma rtnez-Abarca and Peter N Golyshin從基因組和“宏基因組”中尋找新型催化劑Ultra-high-throughput screening based on cell-surface display and fluorescence-activated cell sorting for the identification of novel biocatalystsStefan Becker,Hans—Ulrich Schmoldt,Thorsten Michael Adams,Susanne Wilhelm and Harald Kolmar基于細(xì)胞表面展示及熒光活化細(xì)胞分類的超高通量篩選,尋找新型生物催化劑Improved β-lactam acylases and their use as industrial biocatalystsCharles F Sio and Wim J Quax改良的β-內(nèi)酰胺?;D(zhuǎn)移酶及其作為工業(yè)生物催化劑的應(yīng)用Enzyme catalysed deracemisation and dynamic kinetic resolution reactionsNicholas J Turner酶催化的去消旋化和動(dòng)態(tài)動(dòng)力學(xué)拆分Peroxide-utilizing biocatalysts:structural and functional diversity of heme-containing enzymesIsamu Matsunaga and Yoshitsugu Shiro利用過(guò)氧化物的生物催化劑:含有亞鐵血紅素的酶的結(jié)構(gòu)與功能的多樣性Hydrogenases:active site puzzles and progressFraser A Armstrong氫化酶:活性位點(diǎn)之謎與進(jìn)展EnantioseIective biocatalysis optimized by directed evolutionKarl-Erich Jaeger and Thorsren Eggert通過(guò)定向進(jìn)化優(yōu)化對(duì)映選擇性生物催化劑Evolving haloalkane dehalogenasesDick B Janssen鹵烷烴去鹵化酶的人工進(jìn)化Harnessing microbial activities for environmental cleanupFrank E Loffier.Elizabeth A EdwardS利用微生物活性進(jìn)行環(huán)境凈化BioethanolKevin A Gray,Lishan Zhao and Mark Emptage生物乙醇Chemical diversity through biotransformationsMichael Muiller生物轉(zhuǎn)化帶來(lái)的化學(xué)多樣性Metabolic engineering of Escherichia coil and Corynebacterium glutamicum for biotechnological production of organic acids and amino acidsvolker F Wendisch,Michaet Bott and Bernhard J Eikmanns生產(chǎn)有機(jī)酸和氨基酸的大腸桿菌與谷氨酰胺棒狀桿菌的代謝工程Recent advances in oxygenase-catalyzed biotransformationsVlada B Urlacher and ROIf D Schmid加氧酶催化的生物轉(zhuǎn)化的最新進(jìn)展The soil metagenome-a rich resource for the discovery of novel natural productsRolf Daniel土壤宏基因組一發(fā)現(xiàn)新型天然產(chǎn)物的寶庫(kù)Biocatalysis in pharmaceutical preparation and alterationBarrie Wilkinson and Brian O Bachmann藥物制備與改造中的生物催化High-throughput screening of biocatalytic activity:applications in drug discoveryR Anand Kumar and Douglas S Clark生物催化活性的高通量篩選:在藥物發(fā)現(xiàn)中的應(yīng)用High-throughput screens and selections of enzyme-encoding genesAmir Aharoni,Andrew D Griffiths and Dan S Tawfik酶編碼基因的高通量篩選與精選Predicting enzyme function from protein sequenceJeremy Minshull,Jon E Ness,Claes Gustafsson and Sridhar Govindarajan從蛋白質(zhì)序列預(yù)測(cè)酶功能Synthesis and modifications of carbohydrates,using biotransformationsAlison M Daines,Beatrice A Maltman and Sabine L Flitsch應(yīng)用生物轉(zhuǎn)化進(jìn)行碳水化合物的合成和修飾Whole organism biocatalysisTakeru Ishige,Kohsuke Honda and Sakayu Shimizu全生物體生物催化

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