蛋白質芯片

內(nèi)容概要

人類基因組大規(guī)模測序工作已經(jīng)完成，隨著以功能基因組學和蛋白質組學為主要研究內(nèi)容的后基因時代來臨，蛋白質芯片作為檢測蛋白質存在和運動變化的高效工具，將為本世紀的疾病診斷和治療、新藥開發(fā)、分子生物學、航空航天、司法鑒定、食品衛(wèi)生及環(huán)境監(jiān)測等領域帶來一場革命。    生物芯片技術是一種高通量檢測技術，它包括基因芯片、蛋白質芯片及芯片實驗三大領域。蛋白質芯片以蛋白質代替DNA作為檢測目的物，此基因芯片更接近生命活動的物質層面，以直接測定蛋白質的相對水平及與其他分子在交互作用情況，以定量化的方式反映基因的活動情況，因而蛋白質芯片有著比基因芯片更加直接的應用前景。本書對蛋白質芯片技術進行了全面細致地闡述，包括技術原理、生產(chǎn)方法、表面化學、檢測策略以及抗原、抗體數(shù)據(jù)分析，同時全書圖文并茂，提供了許多生物學應用實例及實驗草案。    本書知識全面，內(nèi)容豐富，集合了蛋白質芯片技術的基礎知識和前沿研究，實用性廣泛，可讀性強。適用于從事生物芯片研究開發(fā)以及生物信息學、蛋白質組學、基因組學、分子生物學、生物化學、細胞生物學、生物技術等相關研究領域的教學科研人員或技術人員參考使用，也可做為研究生教材。

書籍目錄

List of ContributorsPrefaceForewordChapter 1 Principles of Protein MicroarraysChapter 2 Novel strategies in Protein Microarray Generation and DetectionChapter 3 Practical Guide to Protein Microarrays:Assay Systems,Methods,and Algorithms.Chapter 4 Microarrays for the High-Throughput Analysis of Protein-Carbohydrate InteractionsChapter 5 Protein Microarrays:Principles and LimitationsChapter 6 System-Oriented Proteomics Using Protein-Domain MicroarraysChapter 7 colorimetric Microarray Assays for Rheumatoid Arthritis Using a Recombiant Proteome LibraryChapter 8 Academic and Commercial Aspects of Protein Microarray DevelopmentChapter 9 Analyzing Proteins and Protein Modifications with ArrayTubeTM Antiboody MicroarraysChapter 10 Non-Contact Dispensing for Protein MicroarraysChapter 11 High Speed,High Efficiency Protein Printing by BioLPTMChapter 12 Putting the Bio in Biochips:Capture Agents for Protein Microarray Expression Profiling PlatformsChapter 13 Protein Biochips for the Profiling of Allergen-Specific AntibodiesChapter 14 Solid Supports for Protein Microarrays and Related DevicesChapter 15 Protein Microarrays for Biosensor ApplicationsChapter 16 Technological Aspects of Protein Microarrays and NanoarraysChapter 17 Mege-Dense Nanoarrays:The Challenge of Novel Antibody Microarray FormatsChapter 18  INFINITITMSystem:An Automated Multiplexing Protein Microarray PlatformChapter 19 Protein Microarrays for Analysis of Antibody Responses in Animals and HumansChapteG 20 G-Protein Coupled Receptor Microarrays:A Versatile Tool for Drug DiscoveryChapter 21  Proteome-Scale Analysis of the immune Response Against Pathogenic MicroorganismsChapter 22 Development of Protein Microarrays for Drug DiscoveryChapter 23 Development and Applications of functional Protein MicroarraysChapter 24 Enabling Tools for Protein MicroarraysIndes

圖書封面

評論、評分、閱讀與下載

---

    蛋白質芯片 PDF格式下載

---