代謝與細胞工程導(dǎo)論

出版時間：2007-7 出版社：高教分社作者：科他薩頁數(shù)：264

內(nèi)容概要

國外生命科學(xué)優(yōu)秀教材。

書籍目錄

PrefaceListofAbbreviationsIntroductionIntroductoryOutlinesMetabolicandCellularEngineeringintheContextofBioprocessEngineeringToolsforMetabolicandCellularEngineeringEngineeringCellsforSpecificBiotransformationsMetabolicAreasthatHaveBeenSubjectedtoMCEFromDNASequencetoBiologicalFunctionTemporalandSpatialScalinginCellularProcessesScalinginMicrobialandBiochemicalSystemsViewsoftheCellTransductionandIntracellularSignallingSelf-organizedEmergentPhenomenaHomeodynamicsandCoherenceMatterandEnergyBalancesMassBalanceEnergyBalanceCellGrowthandMetaboliteProduction.BasicConceptsMicrobialGrowthunderSteadyandBalancedConditionsMicrobialEnergeticsunderSteadyStateConditionsGrowthKineticsunderSteadyStateConditionsTheDilutionRateandtheGrowth-limitingSubstrateConcentrationBionmassandGrowth-limitingSubstrateConcentrationattheSteadyStateGrowthasaBalanceofFluxesTheFluxCoordinationHypothesisTowardaRationalDesignofCellsRedirectingCentralMetabolicPathwaysunderKineticorThermodynamicControlThermodynamicorKineticControlofFluxunderSteadyStateConditionsKineticandThermodynamicLimitationsinMicrobialSystems.CaseStudiesIncreasingCarbonFlowtoAromaticBiosynthesisinEschericahiacoliMethodsofQuantitationofCellular"ProcessesPerformance"StoichiometryofGrowth：TheEquivalencebetweenBiochemicalStoichiometriesandphysiologicalParametersAGeneralFormalismforMetabolicFluxAnalysisAComparisonbetweenDifferentMethodsofMFAMetabolicFluxesduringBalancedandSteadyStateGrowthBioenergeticandPhysiologicalStudiesinBatchandContinuousCultures.GeneticorEpigeneticRedirectionofMetabolicFluxMetabolicControlAnalysisControlandRegulationTheControlofMetabolitesConcentrationTheTDAApproachasAppliedtotheRationalDesignofMicroorganisms：IncreaseofEthanolProductioninYeastAppendixAAppendixBDynamicAspectsofBioprocessBehaviorTransientandOscillatoryStatesofContinuousCultureMathematicalModelBuildingTransientResponsesofMicrobialCulturestoPerturbationsoftheSteadyStateOscillatoryPhenomenainContinuousCulturesBioprocessDevelopmentwithPlantCellsMCEinPlants：RealitiesandPotentialitiesImprovingPlantsthroughGeneticEngineeringUsingPlantGeneticEngineeringtoProduceHeterologousProteinsToolsfortheManipulationandTransformationofPlantsPlantMetabolism：MatterandEnergyFlowsandtheProspectsofMCAMetabolicCompartmentationinPlantCellsCarbonAssimilation,PartitioningandAllocationCarbonfixationinhigherplantsMCAStudiesinPlantsRegulationandControl：StarchSynthesis,aCaseStudyConcludingRemarksCellularEngineeringOutlineTheGlobalFunctioningofMetabolicNetworksCellularEngineeringGrowthRate,G1PhaseoftheCellCycle,ProductionofMetabolitesandMacromoleculesasTargetsforCellularEngineeringCataboliteRepressionandCellCycleRegulationinYeastProteinProductionasaFunctionofGrowthRateTheSelectiveFunctioningofWholeMetabolicPathwaysisPermissiveforDifferentiationBibliographyIndex

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