分子生物學

內(nèi)容概要

　　“精要速覽系列(Instant Notes Series)”是國外教材“Best Seller”榜的上榜教材。該系列結(jié)構(gòu)新穎，視角獨特；重點明確，脈絡(luò)分明；圖表簡明清晰；英文自然易懂，被國內(nèi)多所重點院校選用作為雙語教材。先鋒版是繼“現(xiàn)代生物學精要速覽”之后推出的跨學科的升級版本。　　本書是該系列中的《分子生物學(第二版)》分冊，全書共19章。新版在原版的基礎(chǔ)上內(nèi)容進行了全面調(diào)整和擴充，增加了若干新專題，如中心法則、細胞周期和細胞凋亡等，書后并附有練習題?！　”緯侵笇Т髮W生快速掌握分子生物學基礎(chǔ)知識的優(yōu)秀教材，也是輔助教師授課的極佳教學參考書，同時可供生命科學相關(guān)專業(yè)的研究生參考。

書籍目錄

AbbreviationsPreface to the second editionPreface to the first editionSection A-Cells and macromoleculesA1 Cellular classificationA2 Subcellular organellesA3 MacromoleculesA4 Large macromolecular assembliesSection B-Protein structureB1 Amino acidsB2 Protein structure and functionB3 Protein anslysisSection C-Properties of nucleic acidsC1 Nucleic acid structureC2 Chemical and physical properties of nucleic acidsC3 Spectroscopic and thermal properties of nucleic acidsC4 DNA supercoilingSection D-Prodaryotic and eukaryotic chromosome structureD1 Prokaryotic chromosome structureD2 Chromatin structureD3 Eukaryotic chromosome structureD4 Genome complexityD5 The flow of genetic informationSection E-DNA replicationE1 DAN replication:an overviewE2 Bacterial DNA replicationE3 The cell cycleE4 Eukaryotic DNA replicationSection F-DNA damage,repair and recombinationF1 MutagenesisF2 DNA damageF3 DNA repairF4 RecombinationSection G-Gene manipulationG1 DNA cloning:an overviewG2 Preparation of plasmid DNAG3 Restriction enzymes and electrophoresisG4 Ligation,transformation and analysis of recombinantsSection H-Cloning vectorsH1 Design of plasmid vectorsH2 Bacteriophage vectorsH3 Cosmids,YACs and BACsH4 Eukaryotic vectorsSection I-Gene libraries and scrreeningI1 Genomic librariesI2 cDNA librariesI3 Screening proceduresSection J-Analysis and uses of cloned DNAJ1 Characterization of clonesJ2 Nucleic acid sequencingJ3 Polymerase chain reactionJ4 Organization of cloned genesJ5 Mutagenesis of cloned genesJ6 Applications of cloningSection K-Transcription in prokaryotesK1 Basic principles of transcriptionK2 Escherichia coli RNA polymeraseK3 The E.coliσpromoterK4 Transcription,initiation,elongation and terminationSection L-Regulation of transcription in prokaryotesL1 The lac operonL2 The trp operonL3 Transcriptional regualation by alternative σfactorsSection M-Transcription in eukaryotesM1 The three RNA polymerases:characterization and functionM2 RNA Pol Ⅰ genes:the ribosomal repeatM3 RNA Pol Ⅲ genes:5S and tRNA transcriptionM4 RNA Pol Ⅱ genes:promoters and enhancersM5 General transcription factors and RNA Pol Ⅱ initiationSection N-Regulation of transcription in eukaryotesN1 Eukaryotic transcription factorsN2 Examples of transcriptional regulationSection O-RNA processing and RNPsO1 rRNA processing and ribosomesO2 tRNA processing,RNase P and ribozymesO3 mRNA processing,hnRNPs and snRNPsO4 Alternative mRNA processingSection P-The genetic code and tRNAP1 The genetic codeP2 tRNA structure and functionSection Q-Protein synthesisQ1 Aspects of protein synthesisQ2 Mechanism of protein synthesisQ3 Initiation in eukaryotesQ4 Translational control and post-translational evenrtsSection R-Bacteriophages and eukaryotic virusesR1 Introduction to virusesR2 BacteriophagesR3 DNA virusesR4 RNA virusesSection S-Tumor viruses and oncogenesS1 Oncogenes found in tumor virusesS2 Categories of oncogenesS3 Tumor suppressor genesS4 ApoptosisFurther readingMultiple choice questionsAnswersIndex

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