胃腸病學(xué)

內(nèi)容概要

本書是世界上最權(quán)威的關(guān)于消化系統(tǒng)疾病診斷、治療的專著，共有169位世界知名教授參加編寫。全書全面描述了消化系統(tǒng)的基礎(chǔ)科學(xué)，包括近年來被廣為重視的分子生物學(xué)和細(xì)胞生物學(xué)，以及臨床常見器官疾患的組織病理、病理生理及實驗室指標(biāo)的異常等，系統(tǒng)介紹了多器官疾?。ㄈ绨滩。┑脑\斷、治療及護(hù)理。本書的特點是以導(dǎo)師的形式對消化系統(tǒng)疾病列出問題，并進(jìn)行了詳盡的討論。    本書可供消化科醫(yī)師、消化專業(yè)研究生生和科研人員學(xué)習(xí)、研究、收藏。

作者簡介

作者：(美國) 費爾德曼(Feldman.M.)

書籍目錄

VOLUME 1  Section Ⅰ  Biology of the Gastrointestinal Tract  Section Ⅱ  Approach to Patients with Symptoms and Signs  Section Ⅲ  Nutrition in Gastroenterology  Section Ⅳ  Topics Involving Multiple Organs  Section Ⅴ Esophagus  Section Ⅵ  Stomacch and Duodenum  Section Ⅶ  Pancreas  Section Ⅷ  Biliary TractVOLUME 2  Section Ⅸ  Liver  Section Ⅹ  Smalland Large Intestines  Section Ⅺ  Vasculature and Supporting Structuresindex

章節(jié)摘錄

The extensive use of immunocytochemistry to localize pep- tides has revealed that individual neurons coexpress and presumably cosecrete multiple peptides,s Furthermore, both peptide and nonpeptide neurotransmitters are invariably coex- pressed. For example, 45% of neurons in the submucosal plexus of the guinea pig intestine coexpress vasoactive intesti- nal polypeptide, dynorphin, galanin, and neuromedin U. What is the physiologic relevance for a neuron to synthesize and possibly release a cocktail of neurotransmitters？ In general, this is an unanswered question. However, examination of the neural regulation of salivary secretion has yielded some in- sight into how two neurotransmitters may work together. Para- sympathetic ganglia innervate secretory cells and smooth mus- cle cells of the salivary ducts, and the nerve endings contain acetylcholine in small vesicles and vasoactive intestinal pep- tide in large vesicles. Stimulation induces release of acetylcho- line and vasoactive intestinal peptide and also increases secre- tion and blood flow. These responses to low-frequency stimulation are mediated by acetylcholine, inasmuch as they are enhanced by eserine （acetylcholinesterase inhibitor） and blocked by atropine （muscarinic receptor antagonist）. At higher frequencies, both effects are enhanced by eserine, but only salivation is blocked by atropine. Thus vasoactive intesti- nal peptide is released by high-frequency stimulation, wherein it is a vasodilator and may enhance the effect of acetylcholine on secretory cells.

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《胃腸病學(xué)(上下冊)》是由科學(xué)出版社出版的。

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