顱腦MR灌注影像 Cerebral MR Perfusion Imaging

內容概要

Cerebral hemodynamics - what are they?    How can I use MRI to measure cerebral perfusion in a clinical setting?    What tumors have high blood volume? Can perfusion imaging help define the ischemic penumbra? What should I do if I want to image perfusion in the presence of a leaky BBB?    From the basic principles of perfusion MR imaging to present clinical applications in the assessment of cerebrovascular diseases and intra-cranial tumors this book provides practical information for newcomers to this technique as well as experienced radiologists.

書籍目錄

Table of ContentsPreface Acknowledgements List of Abbreviations List of Movie Clips Part 1: Technical Considerations   Introduction   Cerebral hemodynamics - what are they?   Perfusion MRI with dynamic susceptibility contrast imaging   Why is magnetic susceptibility so powerful?   Why use contrast agents?   Bolus injection versus slow infusion of contrast agent   Why is the status of the BBB important for Perfusion MRI?   How do I image perfusion in the presence of a leaky BBB?  Advantages of available and future contrast agents   What about non-contrast techniques?   Why use rapid imaging techniques?   Should I use spin echo or gradient echo EPI?   What are the detailed typical parameters for perfusion imaging?    Non-EPI Systems     EPI Systems   Can you tell me more about the optimum contrast agent dose?   Do I need a power injector? How do I use it?   How do I perform a manual injection?  Is the injection volume important?   Is field strength important?   How do I postprocess perfusion images?    Overview     Step 0: Before you start    Step 1 : The initial parameter of concentration versus time    Step 2: Analyzing the curve     Step 3: Creating the maps: CBV     Step 4: Creating the maps: CBF     Step 5: Creating the maps: MTT and other timing maps   What advanced techniques may become important in the future?    Compensation for delay and dispersion     Flow heterogeneity     Average vessel diameter Part 2: Perfusion Imaging in Clinical Practice  Perfusion MRI compared to other routine modalities   Perfusion MRI in cerebrovascular disease     Acute stroke     Stroke pathophysiology and imaging of blood flow     Practical perfusion MRI in acute stroke     Reperfusion    Chronic stroke     Moya-moya     lntraparenchymal hemorrhage   Intracranialtumors    Rationale for perfusion MRI     Diagnosis     Direction of biopsy/intervention     Treatment follow-up   Dementia   Vasospasm   Head trauma   Migraine   Epilepsy   Otherlesions Conclusion References   Selected reading     Perfusion methodology     Clinical applications: ischemia     Clinical applications: tumors     Clinical applications: other areas     Non-contrast perfusion methodology    Perfusion MRI in animal studies   Cited papers Index CD-ROM Instructions

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