Innate Immunity to Pulmonary Infection - No. 279肺感染先天性免疫

內(nèi)容概要

　　Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. 　　Innate Immunity to Pulmonary Infection: 　　Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lung 　　Thoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseases 　　Describes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damage 　　Covers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptors 　　Discusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention ？（vaccination） strategies 　　Includes contributions from an international and interdisciplinary group of experts 　　Innate Immunity to Pulmonary Infection is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics.

書(shū)籍目錄

Symposium on Innate immunity to pulmonary infection, held at the Wolfson Pavillion,University of Cape Town Medical School, South Africa, 28-30 November 2005Editors: Derek J. Chadwick (Organizer) and]amie GoodeThis symposium is based on a proposal made by Siamon Gordon and Gordon BrownSiamon Gordon  Chair's introductionEric D. Bateman and Anamika Jithoo  Lung diseases in South Africa: an  overview  DiscussionPaul D. van Helden, Marlo Mo11er, Chantal Babb, Robin Warren, Gerhard Walzl, Pieter Uys and Eileen Hoal  TB epidemiology and human  genetics  DiscussionDavid P. Speert  Bacterial infections of the lung in normal and immunodeficient patients   DiscussionMalik Peiris  Pathogenesis of avian flu H5N1 and SARS   DiscussionClaudia Montagnoli, Silvia Bozza, Roberta Gaziano, Teresa Zelante, Pierluigi Bonifazi, Silvia Moretti, Silvia Bellocchio, Lucia Pitzurra and Luigina Romani  Immunity and tolerance to Aspergillusfumigatus  DiscussionCecilia Garlanda, Barbara Bottazzi, Giovanni Salvatori, Rita De Santis,Alessia Cotena, Livija Deban, Viriginia Maina, Federica Moalli, Andrea Doni, Tania Veliz-Rodriguez and Alberto Mantovani  Pentraxins in innate immunity and inflammation  DiscussionAnthony W. Segal  How superoxide production by neutrophil leukocytes kills microbes     DiscussionRalph M. Steinman  Linking innate to adaptive immunity through dendritic cells  DiscussionGordon D. Brown  Macrophage receptors and innate immunity: insights from dectin-1  DiscussionBernhard Ryffel, Muazzam Jacobs, Shreemanta Parida, Tania Botha,Dieudonnee Togbe and Valerie Quesniaux  Toll-like receptors and control of mycobacterial infection in mice    DiscussionT. J. Williams and C. t. Weller  Population of lungs by mast cells  DiscussionJohn K. Sheehan, Mehmet Kesimer and Raymond Pickles  Innate immunity and mucus structure and function  DiscussionR. B. Sire, H. Clark, K. Hajela and K. R. Mayilyan  Collectins and host defence  DiscussionBart N. Lambrecht and Leonie S. van Rijt  Infections and asthma pathogenesis: a critical role for dendritic cells?  Discussiont. A. Vella and O. J. Finn  Innate and adaptive immunity in lung cancer  DiscussionSiamon Gordon  Summing-up  Index of contributors  Subject index

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